MISSION® RNAi

Your time is valuable, spend it on discovery!

We provide leading RNA interference (RNAi) tools for gene silencing (siRNA, shRNA, esiRNA, miRNA). MISSION siRNA and esiRNA products offer effective target gene knockdown with reduced off-target effects, while our MISSION shRNA portfolio includes the highly-validated lentiviral-based shRNA libraries of The RNAi Consortium (TRC1/1.5 and TRC2). MISSION miRNA mimics utilize a novel design proven to minimize off-target effects of the sense strand, allowing for accurate functional screens. From basic RNAi to advanced RNAi, the MISSION RNAi portfolio provides you with a comprehensive range of innovative products. Finding RNAi tools for your gene of interest is easy with our Your Favorite Gene search engine.

Screening often lies at the beginning of most discovery research. The network of possible molecular interactions leading to the causal phenotype within a given system, pathway or disease is astounding. It is essential to begin with the most validated and comprehensive RNAi screening tools available. Discovering novel biological interactions leads to a host of characterization and validation studies. To help you with your follow-up validation we offer a large variety of custom options and services. Spend your time on discovery!

Upcoming events

RNAi & miRNA Europe

The annual RNAi & miRNA Europe is Europe's largest conference & exhibition dedicated to RNA interference. This year event will take place in ...

Location:
Dublin, Ireland

Dates:
14 – 15 September 2010

Neuroscience 2010

Neuroscience 2010, the 40th annual meeting of the Society for Neuroscience, will take place between 13-17 in San Diego, California Scientists will con ...

Location:
San Diego, California, USA

Dates:
13 – 17 November 2010

April 20, 2010 @ 9:19 am by Sigma Aldrich
Sigma-Aldrich® (NASDAQ: SIAL), today announced an extension to its award-winning CompoZr® product offering with the global release of the CompoZr Targeted Int ...
April 19, 2010 @ 8:36 am by Sigma Aldrich
Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich® (NASDAQ: SIAL), today introduced the world's first p53 ...
April 13, 2010 @ 4:15 pm by Sigma Aldrich
Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich® (NASDAQ: SIAL), today announced a significant expansion to its we ...
August 12, 2010 @ 7:00 pm
BOTHELL, WA--(Marketwire - August 12, 2010) - Marina Biotech, Inc. (NASDAQ: MRNAD), formerlyMDRNA, Inc., a leading RNAi-based drug discovery and development com ...
August 12, 2010 @ 7:00 pm
RXi Pharmaceuticals Corp., a RNAi-based therapeutic discovery and development company, has reported its financial results for the second quarter ended June 30. ...
August 12, 2010 @ 2:04 pm
Researchers involved in the Australia and New Zealand Multiple Sclerosis Genetics Consortium identified two T-cell related miRNAs that are under-expressed in pe ...
August 13, 2010 @ 3:34 pm by Sigma BioBlogs
The Where Bio Begins/Sigma Life Science marketing department is housed along with Sigma’s Research and Development scientists. Every day, we have the pleasu ...
August 6, 2010 @ 4:42 pm by Sigma BioBlogs
I had an idea for my next blog entry. Hmmm. What was the topic? Who doesn’t pause to ask themselves that question only to find that they do not have ...
July 30, 2010 @ 4:38 pm by Sigma BioBlogs
When we upgraded our Your Favorite Gene site, we added a full PubMed search, and made keyword relationships more obvious by adding a tag cloud. ...

Your favourite gene

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